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Tadalis SX 20 mg works by blocking the enzyme phosphodiesterase type 5 (PDE5). Normally, this enzyme breaks down cyclic guanosine monophosphate (cGMP), a chemical responsible for relaxing smooth muscles in blood vessels. When PDE5 is inhibited, cGMP levels stay higher for longer, leading to better relaxation of penile blood vessels and increased blood flow during sexual arousal. Tadalis SX 20 mg should not be used with nitrate medicines (used for chest pain), as this can cause a dangerous drop in blood pressure. Caution is also needed in people with heart, liver, or kidney conditions.

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